SubtiBank SubtiBank
yqiD [2019-07-04 12:55:26]
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yqiD [2019-07-04 12:55:26]

geranyltransferase
Locus
BSU24280
Isoelectric point
5.02
Molecular weight
29.59 kDa
Protein length
296 aa Sequence Blast
Gene length
891 bp Sequence Blast
Function
biosynthesis of peptidoglycan and teichoic acid
Product
geranyltransferase
Essential
no
E.C.
2.5.1.10
Synonyms
ispA
Outlinks
KEGGBsubCycSubtiListUniProt

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Lipid metabolism → Biosynthesis of lipids → Biosynthesis of isoprenoids

    • Gene

    Coordinates
    2,525,789 → 2,526,679

    Phenotypes of a mutant

  • The mutation of yqiD predisposes cells to grow without a wall PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • dimethylallyl pyrophosphate 2 isopentanyl pyrophosphate → farnasyl pyrophosphate

    • Paralogous protein(s)

  • HepT

    • Modification

  • None

    • Cofactors

  • Magnesium

    • Structure

  • 1RQI: IspA from E. coli. Co-crystal with substrate isopentyl pyrophosphate and substrate analogue dimethyallyl S-thiolodiphosphate PubMed

    • Biological materials

    Mutant

  • BKE24280 (ΔyqiD::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CCGGTCCGCCAGAAAGCTCG, downstream forward: _UP4_TAAAACGATCCTAATTTGAA
  • BKK24280 (ΔyqiD::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CCGGTCCGCCAGAAAGCTCG, downstream forward: _UP4_TAAAACGATCCTAATTTGAA

    • References

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